Conference - P4FIFTY

From June 24, 2015 until June 26, 2015

Over recent years it has become apparent that the power of cytochromes P450s can be recruited for the clean, green chemical synthesis of important intermediates in the bulk chemical, pharmaceutical and agrochemical industries. P450s are able to catalyse a variety of different reactions on various substrates, performing highly regio- and stereo-selective reactions on complex chemical substrates, which cannot be performed with the same efficiencies using chemical approaches.

However, industrial application of P450s has been frustrated by natural limitations such as low activity, insoluble gene expression and the dependence on auxiliary electron transport proteins for full activity, each of which militate against the scale-up of P450-catalysed reactions. The conference will focus on the development of new strategies for the improvement of P450 systems, especially for application in the field of terpenoid production.

The aim of the conference is to promote collaboration between European Academic institutions and industry and to give the students of the network and other young attendees the opportunity to meet potential employers and to broaden their scope of potential employment.

Keynote industrial speakers will include:
Simon Charnock, Prozomix
Claus Lattemann, Sanofi
Monika Mueller, DSM
Liam Evans, Hypha Discoveries

Audience: limited to 100 participants, members of the consortium, representatives of European companies and a limited number of external attendees.

This conference is co-organised by dr Danièle Werck, USIAS-FRIAS Fellow 2013.

P4FIFTY is an FP7 funded European Marie Curie Training network of academic and industrial researchers looking to develop enzymatic methods for green oxidation chemistry through the isolation, redesign and application of cytochrome P450 enzymes. P4FIFTY website: http://www.p4fifty.eu/